• The NMP® (Natural Matrix Protein®) Process unlocks natural growth factors
• Ambient temperature storage with a 5-year shelf life
• Available in FiberMatrix and Micro Particulates

INDUCE Oi-9 Bioimplants are advanced allografts that harness natural growth factors to replicate the body’s innate healing capabilities by the NMP® (Natural Matrix Protein®) Process.

The proprietary NMP Process unlocks growth factors from the bone matrix and makes them bioavailable. (1) NMP processing is a multi-step process which includes removing a majority of the mineral component.

INDUCE Oi-9 Bioimplants contain growth factors and BMPs to support the complex cascade of bone regeneration including BMP-2, BMP-7, BMP-9, TGF-B1, PDGF, VEGF, and IGF-2.

The NMP process enhances their bioavailability as shown through analytical testing. Multiple bone morphogenic proteins, growth and differentation factors play a critical role in bone formation. These growth factors work synergistically to promote bone formation. (2)

The INDUCE Oi-9 Bioimplant has been shown to form more bone of a better quality than rhBMP-2 in animal studies.

• FiberMatrix is made from NMP® (Natural Matrix Protein®) Processed human cortical fiber and particulates
• Micro Particulates made from NMP (Natural Matrix Protein) Processed human cortical particulates

The NMP Process unlocks growth factors naturally found in bone, making them bioavailable for bone regeneration.

Upon hydration, INDUCE Oi-9 becomes a moldable, easy to place putty and may be used alone or in combination with other regenerative materials.

INDUCE Oi-9 is terminally sterilized with a 5-year shelf life and stored at ambient temperature.

• Saving teeth and saving implants in the compromised patient
• Ridge Augmentation
• Periodontal Defects
• Furcation Defects
• Peri-Implantitis
• Sinus Elevation

INDUCE Oi-9 Bioimplants are freeze dried and sterile and should be stored at ambient temperature. To rehydrate and prepare product for use, cover allograft with whole blood, lactated ringers or normal saline. Please see Instructions for Use included with each product for more information.

(1) Statistically significant, p<0.01

(2) Li P., et al. Synergistic and sequential effects of BMP-2, bGF and VEGF on osteogenic differentiation of rat osteoblasts. J Bone Miner Metab 32, 627-635 (2014).

(3) Kohen Y., Shivanna S. and Peel SAF. Evaluation of Natural Matrix Proteins (NMP) Bone Allograft in vitro and in vivo. ASBMR. LB SUN-908, 2022. Natural Bone Matrix Growth Factors Locked in Bone Matrix, Limited Osteoinductive Activity NMP Processing INDUCE Oi-9 Growth Factors Unlocked and Bioavailable