NuOss natural cancellous and cortical bone matrix is produced by the removal of all organiccomponents from bovine bone. Due to its natural porous structure, NuOss is physically andchemically comparable to the mineralized matrix of human bone.The proprietary manufacturing process of NuOss allows for maintenance of the naturally occurring bone mineral structure, including macroscopic and microscopic structures. Due to this trabecular architecture with interconnecting macro and micro pores, the ingrowth of new bone and associated vascularization at the grafting site is optimized.NuOss may be used with autogenous bone where there is an insufficient quantity of bone to fulfill the needs of the proposed surgical procedure.

• Handling: The structure of NuOss aids in particulate hydration and delivery of the product to the defect.
• Particle Distribution: NuOss maximizes the distribution of the preferred particle sizing within desired ranges.
• Particle Structure and Porosity: NuOss maintains the high porosity and trabecular structureof natural mineralized bone and maximizes the potential for angiogenesis.